03 Nov 2025

"Manifold Bio Announces Strategic Collaboration with Roche to Advance AI-Driven Neurological Drug Discovery"

"Manifold Bio has entered a strategic research collaboration and licensing agreement with Roche to develop advanced blood-brain barrier (BBB) shuttles for treating neurological and neurodegenerative diseases. The partnership leverages Manifold's AI-driven drug discovery platform and proprietary tissue-targeting technologies. Legal counsel for the transaction was provided by Latham & Watkins."

Latham & Watkins participated in the transaction, advising Manifold Bio in its strategic research collaboration and license agreement with Roche. The transaction involves a partnership between Manifold Bio, a platform therapeutics company pioneering AI-guided drug discovery, and Roche to apply Manifold's proprietary tissue-targeting shuttle portfolio and mDesign AI-driven in vivo discovery engine to develop next-generation BBB shuttles for neurological and neurodegenerative disease treatments. The Latham & Watkins team included Bay Area partner Kate Hillier (corporate), associate Arun Mohan (corporate), New York partner John Pierce (arbitration), Bay Area partner Grace Lee (tax), and associate Derek Gumm (tax).
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